Cozette P, Laxenaire M C, Floquet J, Belleville F, Picard J M
Ann Anesthesiol Fr. 1976;17(5):577-84.
71 male rats (Whitstar strain) are submitted to restraint. 37 of them were receiving twice an injection of 10 000 I.U. of vitamin A in order to protect them against the occurence of stress ulcer. Untreated animals are used as controls. Incidence of obtained ulcer is compared with the variation of vitamin A serum concentration, classicaly decreased in stress. Analysis of individual results shows that, if parenteral administration was followed either by restitution of the initial serum concentration, or by its increase, the treatment was efficient in 64 p. 100 of the cases.
71只雄性大鼠（惠斯塔尔品系）被施以约束。其中37只大鼠接受了两次10000国际单位维生素A的注射，以保护它们免受应激性溃疡的发生。未治疗的动物用作对照。将获得的溃疡发生率与维生素A血清浓度的变化进行比较，在应激状态下维生素A血清浓度通常会降低。对个体结果的分析表明，如果肠胃外给药后初始血清浓度恢复或升高，那么在64%的病例中治疗是有效的。
