Sjoberg S A, Neitz M, Balding S D, Neitz J
Department of Cellular Biology and Anatomy, Medical College of Wisconsin, Milwaukee 53226-0509, USA.
Vision Res. 1998 Nov;38(21):3213-9. doi: 10.1016/s0042-6989(97)00367-2.
To directly test the hypothesis that only two pigment genes are expressed from the X-chromosome array, we examined expressed M and L pigment gene sequences from > 100 male eye donors. In this sample, there were eight men who expressed high levels of more than one L pigment gene in addition to M pigment genes. The fact that these eyes expressed both L and M pigment genes at significant levels suggests they were from men with normal colour vision. We reject the hypothesis that only two pigment genes from one X-chromosome array can be expressed.
为了直接验证仅从X染色体阵列中表达两个色素基因这一假设，我们检测了来自100多名男性眼捐赠者的已表达的M和L色素基因序列。在这个样本中，有8名男性除了表达M色素基因外，还高水平表达了不止一种L色素基因。这些眼睛同时显著表达L和M色素基因这一事实表明，它们来自具有正常色觉的男性。我们拒绝接受仅能从一个X染色体阵列中表达两个色素基因这一假设。
