Chakravarty K, Sarma D, al-Jafari M S
Department of Rheumatology, Warrington Hospital NHS Trust, Cheshire, UK.
Int J Clin Pract. 1998 Sep;52(6):441-2.
We describe a patient with Sjögren's syndrome who died from undiagnosed adrenocortical failure. A positive test for adrenocortical antibody, performed pre-terminally, suggested the underlying diagnosis, which was subsequently confirmed at post-mortem. This case highlights the rare association of Sjögren's syndrome with occult adrenocortical failure. Perhaps a greater awareness of this association and more frequent serological screening are necessary to prevent a fatal outcome.
