Mann R B
Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland 21287, USA.
Am J Clin Pathol. 1999 Jan;111(1 Suppl 1):S144-50.
Aggressive B-cell lymphomas, including diffuse large cell, Burkitt, and lymphoblastic types, may affect a wide variety of extranodal sites. Up to 40% of these tumors are initially diagnosed in extranodal locations. Regardless of site, these tumors have many histologic similarities; however, some clinical, cytologic, immunologic, and etiologic features of these tumors seem to be distinctive for particular sites of extranodal presentation. In accordance primarily with the extranodal locations presented at the Society for Hematopathology Fourth Slide Workshop on Extranodal Hematopoietic/Lymphoid Disorders (Excluding Bone Marrow and Spleen), the distinctive features of the aggressive B-cell lymphomas of the mediastinum, breast, bone, skin, and body cavities as well as the rare, but primarily extranodal intravascular lymphomatosis, will be discussed.
侵袭性B细胞淋巴瘤，包括弥漫大细胞型、伯基特型和淋巴母细胞型，可累及多种结外部位。这些肿瘤中高达40%最初在结外部位被诊断出来。无论部位如何，这些肿瘤在组织学上有许多相似之处；然而，这些肿瘤的一些临床、细胞学、免疫学和病因学特征在特定的结外表现部位似乎是独特的。主要根据在血液病理学协会关于结外造血/淋巴系统疾病（不包括骨髓和脾脏）的第四届幻灯片研讨会上呈现的结外部位，将讨论纵隔、乳腺、骨骼、皮肤和体腔侵袭性B细胞淋巴瘤以及罕见但主要为结外血管内淋巴瘤病的独特特征。
