Meagher D J, O'Hanlon D, O'Mahony E, Casey P R, Trzepacz P T
St. Ita's Hospital, Portrane, County Dublin, Republic of Ireland.
J Geriatr Psychiatry Neurol. 1998 Fall;11(3):146-9; discussion 157-8. doi: 10.1177/089198879801100305.
This study describes the symptom profile of 46 patients with delirium seen as consecutive referrals to a consultation-liaison psychiatry service. The relationship between symptoms rated on the Delirium Rating Scale (DRS) and delirium subtypes defined according to three putative etiologic groups are described. The relationship between etiologic groups and motoric subtype of the delirium episode is also described. Drug-related cases had the highest total DRS score and higher scores than the anticholinergic group for perceptual changes, delusions, psychomotor disturbance, and mood lability. Drug-related cases had higher scores than both the anticholinergic and infectious/electrolyte group for changes in sleep-wake cycle and fluctuation of symptoms. Those from the anticholinergic etiologic group were more likely to fit the hypoactive motoric subtype. Although our findings are tentative, etiologic categories may present with different symptom profiles, which may be associated with differing treatment responsiveness and course.
本研究描述了46例谵妄患者的症状特征，这些患者是作为连续转诊至会诊联络精神病学服务部门的病例。文中描述了根据三种假定病因组定义的谵妄亚型与谵妄评定量表（DRS）所评定症状之间的关系。还描述了病因组与谵妄发作运动亚型之间的关系。药物相关病例的DRS总分最高，在感知改变、妄想、精神运动障碍和情绪不稳定方面的得分高于抗胆碱能组。在睡眠-觉醒周期改变和症状波动方面，药物相关病例的得分高于抗胆碱能组和感染/电解质组。来自抗胆碱能病因组的患者更有可能符合运动减退型运动亚型。尽管我们的研究结果是初步的，但病因类别可能呈现出不同的症状特征，这可能与不同的治疗反应性和病程有关。
