Gold G E, Bergman A G, Pauly J M, Lang P, Butts R K, Beaulieu C F, Hargreaves B, Frank L, Boutin R D, Macovski A, Resnick D
Department of Radiology, UCSD and VA San Diego Healthcare System, California, USA.
Top Magn Reson Imaging. 1998 Dec;9(6):377-92.
Cartilage injury resulting in osteoarthritis is a frequent cause of disability in young people. Osteoarthritis, based on either cartilage injury or degeneration, is a leading cause of disability in the United States. Over the last several decades, much progress has been made in understanding cartilage injury and repair. Magnetic resonance (MR) imaging, with its unique ability to noninvasively image and characterize soft tissue, has shown promise in assessment of cartilage integrity. In addition to standard MR imaging methods, MR imaging contrast mechanisms under development may reveal detailed information regarding the physiology and morphology of cartilage. MR imaging will play a crucial role in assessing the success or failure of therapies for cartilage injury and degeneration.
导致骨关节炎的软骨损伤是年轻人致残的常见原因。基于软骨损伤或退变的骨关节炎是美国致残的主要原因。在过去几十年里,在理解软骨损伤和修复方面取得了很大进展。磁共振(MR)成像具有无创成像和表征软组织的独特能力,在评估软骨完整性方面显示出前景。除了标准的MR成像方法外,正在开发的MR成像对比机制可能会揭示有关软骨生理和形态的详细信息。MR成像在评估软骨损伤和退变治疗的成败中将发挥关键作用。