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莱姆病伴单侧间质性角膜炎。

Lyme disease associated with unilateral interstitial keratitis.

作者信息

Miyashiro M J, Yee R W, Patel G, Ruiz R S

机构信息

Department of Ophthalmology and Visual Science, The University of Texas Medical School at Houston, 77030, USA.

出版信息

Cornea. 1999 Jan;18(1):115-6.

PMID:9894947
Abstract

PURPOSE

To report a case of Lyme disease that presented with a single nummular unilateral interstitial keratitis.

METHODS

Case report and review of the literature.

RESULTS

A 57-year-old black man who had contact with freshly killed deer had a chief complaint of foreign-body sensation in his right eye (OD) that had been diagnosed and treated for herpes simplex stromal keratitis. The patient underwent a systemic workup for interstitial keratitis. All results including RPR and MHA-TP were negative except for Lyme antibody titer (enzyme-linked immunosorbent assay [ELISA]) 178 U/ml (normal, <159 U/ml).

CONCLUSION

Interstitial keratitis from Lyme disease has been regarded as a bilateral disease in the literature. We present this infrequent ocular manifestation of Lyme disease as a rare single nummular unilateral presentation.

摘要

目的

报告一例莱姆病,其表现为单个钱币状单侧间质性角膜炎。

方法

病例报告及文献复习。

结果

一名57岁的黑人男性,曾接触刚被杀死的鹿,主要主诉右眼有异物感,该眼曾被诊断为单纯疱疹性基质性角膜炎并接受治疗。患者接受了间质性角膜炎的全身检查。除莱姆抗体滴度(酶联免疫吸附测定[ELISA])为178 U/ml(正常,<159 U/ml)外,包括快速血浆反应素环状卡片试验(RPR)和梅毒螺旋体血凝试验(MHA-TP)在内的所有结果均为阴性。

结论

文献中一直将莱姆病引起的间质性角膜炎视为双侧疾病。我们将这种莱姆病罕见的眼部表现呈现为罕见的单个钱币状单侧表现。

相似文献

1
Lyme disease associated with unilateral interstitial keratitis.莱姆病伴单侧间质性角膜炎。
Cornea. 1999 Jan;18(1):115-6.
2
Etiology of immune stromal (interstitial) keratitis.免疫性基质(间质)角膜炎的病因
Cornea. 1998 May;17(3):278-81.
3
Unilateral posterior stromal keratitis possibly secondary to Lyme disease.单侧后部基质角膜炎可能继发于莱姆病。
Cornea. 2013 Feb;32(2):196-8. doi: 10.1097/ICO.0b013e318274d85d.
4
Monolateral chorioretinitis with multiple foci in one case of Lyme disease.莱姆病一例出现单眼脉络膜视网膜炎伴多个病灶。
Ann Ophthalmol. 1993 Jul;25(7):257-61.
5
Orbital myositis associated with Borrelia burgdorferi (Lyme disease) infection.与伯氏疏螺旋体(莱姆病)感染相关的眼眶肌炎。
Ophthalmology. 2004 May;111(5):1023-8. doi: 10.1016/j.ophtha.2003.08.032.
6
Adult-onset syphilitic stromal keratitis.成人期梅毒基质性角膜炎。
Am J Ophthalmol. 2006 Feb;141(2):319-21. doi: 10.1016/j.ajo.2005.09.015.
7
In vivo confocal microscopy: a new possibility to confirm the diagnosis of Borrelia keratitis?
Cornea. 1996 Nov;15(6):639-40.
8
Diffuse lamellar keratitis associated with gonococcal keratoconjunctivitis 3 years after laser in situ keratomileusis.准分子激光原位角膜磨镶术后3年发生的与淋菌性角膜结膜炎相关的弥漫性层间角膜炎。
J Cataract Refract Surg. 2007 Feb;33(2):323-5. doi: 10.1016/j.jcrs.2006.09.029.
9
Lyme disease atypically presenting with a singular symptom: Unilateral chorioretinitis.莱姆病表现为单一症状:单侧脉络膜炎。
Eur J Ophthalmol. 2021 Mar;31(2):NP151-NP156. doi: 10.1177/1120672120962055. Epub 2020 Oct 1.
10
Persistence of immunoglobulin M or immunoglobulin G antibody responses to Borrelia burgdorferi 10-20 years after active Lyme disease.活动性莱姆病后10 - 20年,对伯氏疏螺旋体的免疫球蛋白M或免疫球蛋白G抗体反应持续存在。
Clin Infect Dis. 2001 Sep 15;33(6):780-5. doi: 10.1086/322669. Epub 2001 Aug 10.

引用本文的文献

1
A Next-Generation Sequencing-Based Molecular Approach to Characterize a Tick Vector in Lyme Disease.基于下一代测序的分子方法鉴定莱姆病中的蜱传媒介。
OMICS. 2018 Aug;22(8):565-574. doi: 10.1089/omi.2018.0089.