一个调节组织对白色念珠菌抗性的基因（Carg1）定位于小鼠的14号染色体上。
A gene (Carg1) that regulates tissue resistance to Candida albicans maps to chromosome 14 of the mouse.
作者信息
Ashman R B
机构信息
School of Dentistry, University of Queensland, Brisbane, Qld., 4072, Australia.
出版信息
Microb Pathog. 1998 Dec;25(6):333-5. doi: 10.1006/mpat.1998.0240.
Tissue susceptibility and resistance to infection with the yeast Candida albicans is genetically regulated. Analysis of the strain distribution pattern of the C. albicans resistance gene (Carg1) and additional gene and DNA segment markers in the AKXL recombinant inbred (RI) set showed that 13/15 RI strains were concordant for Carg1, Tcra and Rib1. Therefore, Carg1 is probably located within a 17 cM segment of chromosome 14, within approximately 4 cM of the other two genes.
组织对白色念珠菌感染的易感性和抵抗力是由基因调控的。对AKXL重组近交（RI）系中白色念珠菌抗性基因（Carg1）以及其他基因和DNA片段标记的菌株分布模式分析表明，15个RI菌株中有13个在Carg1、Tcra和Rib1方面是一致的。因此，Carg1可能位于14号染色体上17厘摩的区段内，距其他两个基因约4厘摩。
Zotero 插件