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肾细胞癌胸内转移的发生率及分布

Incidence and distribution of intrathoracic metastases from renal cell carcinoma.

作者信息

Kutty K, Varkey B

出版信息

Arch Intern Med. 1984 Feb;144(2):273-6.

PMID:6696563
Abstract

Chest roentgenographic findings in 46 patients with renal cell carcinoma were analyzed and correlated to clinical and pathologic findings. Twenty-five patients (54.3%) had intrathoracic metastasis, 17 (37%) of whom had roentgenographic evidence of intrathoracic metastasis at the time of initial diagnosis. Lung metastasis was present in 14 patients (30%), alone in ten patients and along with mediastinal or pleural metastasis in four patients. Mediastinal lymph node metastasis was present in 13 patients (28.2%) and was distributed in the following locations: bilateral hila, six; right hilum, two; right paratracheal area, two; left hilum, one; left paratracheal area, one; and left hilum and right paratracheal area, one. Mediastinal lymph node enlargement was the sole roentgenographic finding in six patients (13%). Metastasis to the lungs or mediastinum may already be present in more than a third of the patients with renal cell carcinoma at the time of diagnosis. Mediastinal lymph node metastasis from renal cell carcinoma occurs more frequently than previously reported and may be the only chest roentgenographic manifestation of the disease.

摘要

对46例肾细胞癌患者的胸部X线检查结果进行了分析,并与临床和病理结果相关联。25例患者(54.3%)发生胸内转移,其中17例(37%)在初次诊断时即有胸内转移的X线证据。14例患者(30%)出现肺转移,其中10例为单纯肺转移,4例伴有纵隔或胸膜转移。13例患者(28.2%)出现纵隔淋巴结转移,分布于以下部位:双侧肺门,6例;右肺门,2例;右气管旁区域,2例;左肺门,1例;左气管旁区域,1例;左肺门和右气管旁区域,1例。纵隔淋巴结肿大是6例患者(13%)唯一的X线表现。在肾细胞癌患者诊断时,超过三分之一的患者可能已经出现肺或纵隔转移。肾细胞癌纵隔淋巴结转移的发生率比之前报道的更高,可能是该疾病唯一的胸部X线表现。

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Transl Oncol. 2017 Jun;10(3):304-310. doi: 10.1016/j.tranon.2017.01.016. Epub 2017 Mar 16.
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Solitary pleural metastasis from renal cell carcinoma: a case of successful resection.肾细胞癌孤立性胸膜转移:一例成功切除病例
Surg Case Rep. 2015;1(1):36. doi: 10.1186/s40792-015-0039-z. Epub 2015 Apr 23.
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Metastatic renal clear cell carcinoma mimicking stage IV lung cancer.
转移性肾透明细胞癌酷似IV期肺癌。
Int Urol Nephrol. 2003;35(1):15-7. doi: 10.1023/a:1025920617143.
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Metastatic renal cell carcinoma mimicking pleural mesothelioma.转移性肾细胞癌酷似胸膜间皮瘤。
Thorax. 1987 Nov;42(11):901-2. doi: 10.1136/thx.42.11.901.