Pal A K, Gupta T, Chatterjee A
Acta Endocrinol (Copenh). 1976 Nov;83(3):506-11.
A single consistent luteolytic dose of 10 IU PMSG given on day 5 of pregnancy caused complete resorption of foetuses and placentae associated with a polyfollicular ovarian state in rats. Concomitant treatment with progesterone or prolactin given concurrently with PMSG was found to overcome the antifertility efficacy of PMSG and maintained the endocrine balance favouring pregnancy maintenance. It was postulated that the PMSG-induced ovarian polyfolliculogenesis might be responsible for luteolysis of the corpus luteum gravidarum.
在妊娠第5天给予大鼠单次10国际单位孕马血清促性腺激素（PMSG）的溶黄体剂量，可导致胎儿和胎盘完全吸收，同时伴有大鼠多卵泡卵巢状态。发现与PMSG同时给予孕酮或催乳素进行联合治疗，可克服PMSG的抗生育作用，并维持有利于妊娠维持的内分泌平衡。据推测，PMSG诱导的卵巢多卵泡发生可能是妊娠黄体溶解的原因。
