自然分娩或引产后宫-胎盘单位内组织中前列腺素E2和前列腺素F2α的浓度。

The concentrations of prostaglandin E2 and prostaglandin F2alpha in tissues within the fetoplacental unit after spontaneous or induced labour.

作者信息

Willman E A, Collins W P

出版信息

Br J Obstet Gynaecol. 1976 Oct;83(10):786-9. doi: 10.1111/j.1471-0528.1976.tb00745.x.

DOI:10.1111/j.1471-0528.1976.tb00745.x

Abstract

The concentrations of prostaglandin E2 (PGE2) and prostaglandin F2alpha (PGF2alpha) were measured by radioimmunoassay in portions of umbilical cord, placenta, amnion, chorion and decidua. The samples were obtained during 12 confinements immediately after the delivery of a healthy baby. Labour had either occurred spontaneously (6 subjects) or had been induced approximately two weeks after the estimated date of delivery. The results showed that the concentration of PGE2 was significantly higher (Student's 't' test) in samples of placenta (P less than 0-05), decidua (P less than 0-025), umbilical cord (P less than 0-0125) and amnion (P less than 0-0025), from those patients who had started labour spontaneously. In contrast, the concentration of PGF2alpha was only raised to a significant extent (P less than 0-025) in the amnion. The findings are discussed.

摘要

采用放射免疫分析法测定了部分脐带、胎盘、羊膜、绒毛膜和蜕膜中前列腺素E2（PGE2）和前列腺素F2α（PGF2α）的浓度。样本取自12例健康婴儿出生后立即采集的分娩组织。其中6例为自然分娩，另外6例为在预计分娩日期约两周后引产。结果显示，自然分娩患者的胎盘（P<0.05）、蜕膜（P<0.025）、脐带（P<0.0125）和羊膜（P<0.0025）样本中PGE2浓度显著更高（采用学生t检验）。相比之下，PGF2α浓度仅在羊膜中有显著升高（P<0.025）。对这些研究结果进行了讨论。