来自大鼠肝脏、兔肺和猪肺的溶血双磷脂酸的立体化学构型。
The stereochemical configuration of lysobisphosphatidic acid from rat liver, rabbit lung and pig lung.
作者信息
Joutti A, Brotherus J, Renkonen O, Laine R, Fischer W
出版信息
Biochim Biophys Acta. 1976 Nov 19;450(2):206-9. doi: 10.1016/0005-2760(76)90092-8.
Lysobisphosphatidic acid known also as bis(monoacyl-glycerol)phosphate, was isolated from liver of rats treated with Triton WR1339, and from rabbit and pig lung. Alkaline hydrolysates of all these samples of lysobisphosphatidic acid were essentially similar and contained phosphorus, total glycerol, free glycerol, total glycerophosphates, beta-glycerophosphate, total alpha-glycerophosphates, sn-glycero-1-phosphate and sn-glycero-3-phosphate in a molar ratio of 1.0 : 2.0 : 1.0 : 1.0 :0.6 : 0.4 : 0.38 : 0.04. This proves that the backbone of the principal lysobisphosphatidic acid from all three sources has the structure of 1-sn-glycerophospho-1-sn-glycerol.
溶血双磷脂酸，也称为双（单酰甘油）磷酸酯，是从用曲拉通WR1339处理的大鼠肝脏以及兔和猪肺中分离出来的。所有这些溶血双磷脂酸样品的碱性水解产物基本相似，且含有磷、总甘油、游离甘油、总甘油磷酸酯、β-甘油磷酸酯、总α-甘油磷酸酯、sn-甘油-1-磷酸酯和sn-甘油-3-磷酸酯，其摩尔比为1.0 : 2.0 : 1.0 : 1.0 : 0.6 : 0.4 : 0.38 : 0.04。这证明来自所有这三种来源的主要溶血双磷脂酸的主链具有1-sn-甘油磷酸-1-sn-甘油的结构。
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