[血清体液因子——精神分裂症患者外周血淋巴细胞生理状态改变的原因]

[Serum humoral factors--cause of the altered physiologic state of peripheral blood lymphocytes in schizophrenic patients].

作者信息

Lideman R R, Babaian N G

出版信息

Biull Eksp Biol Med. 1976 Sep;82(9):1047-50.

Abstract

Statistically significant correlations were revealed between the following: the percentage content in the lymphocyte cultures of patients suffering from schizophrenia of cells responding to stimulation with phytohemagglutinin (PHA) by DNA synthesis, and the percentage in the white blood cell cultures of healthy donors of lymphocytes failing to respond to the PHA stimulation by the DNA synthesis as a result of cultivation of these cells in a medium containing the blood serum (20%) of schizophrenic patients. Similar correlation was revealed between the percentage content in cultures of the white blood cells of schizophrenic patients of adhesive lymphocytes and the percentage of adhesive lymphocytes in the white blood cell cultures of healthy donors in cultivation of these cells in a medium containing the blood serum (20%) of schizophrenic patients. The data obtained confirmed a supposition that the altered physiological condition of the peripheral blood lymphocytes of patients suffering from schizophrenia was caused by the factors contained in the blood serum of these patients.

摘要

在以下各项之间发现了具有统计学意义的相关性

精神分裂症患者淋巴细胞培养物中通过DNA合成对植物血凝素（PHA）刺激作出反应的细胞的百分比含量，以及健康供体白细胞培养物中由于在含有精神分裂症患者血清（20%）的培养基中培养这些细胞而未能通过DNA合成对PHA刺激作出反应的淋巴细胞的百分比。在精神分裂症患者白细胞培养物中黏附淋巴细胞的百分比含量与健康供体白细胞培养物中在含有精神分裂症患者血清（20%）的培养基中培养时黏附淋巴细胞的百分比之间也发现了类似的相关性。所获得的数据证实了一种假设，即精神分裂症患者外周血淋巴细胞生理状态的改变是由这些患者血清中所含的因素引起的。

相似文献

1

[Serum humoral factors--cause of the altered physiologic state of peripheral blood lymphocytes in schizophrenic patients].[血清体液因子——精神分裂症患者外周血淋巴细胞生理状态改变的原因]

Biull Eksp Biol Med. 1976 Sep;82(9):1047-50.

2

[Effect of schizophrenic patients' serum on the physiological state of lymphocytes under in vitro conditions].[精神分裂症患者血清在体外条件下对淋巴细胞生理状态的影响]

Zh Nevropatol Psikhiatr Im S S Korsakova. 1977;77(9):1361-4.

3

[Effect of schizophrenic patients' serum on DNA synthesis in cultures of PHA stimulated lymphocytes].[精神分裂症患者血清对PHA刺激的淋巴细胞培养物中DNA合成的影响]

Zh Nevropatol Psikhiatr Im S S Korsakova. 1977;77(9):1357-60.

4

[Effect of blood serum from schizophrenic patients and from normal donors on DNA synthesis in lymphocytes].[精神分裂症患者及正常献血者血清对淋巴细胞DNA合成的影响]

Biull Eksp Biol Med. 1976;81(4):430-2.

5

[Determination of the content of DNA synthesizing lymphocytes in PHA stimulated blood cultures form schizophrenic patients].[精神分裂症患者PHA刺激的血液培养物中DNA合成淋巴细胞含量的测定]

Zh Nevropatol Psikhiatr Im S S Korsakova. 1975;75(6):885-8.

6

[Role of serum factors in decreasing the reaction of peripheral blood lymphocytes in schizophrenia to PHA stimulation].[血清因子在降低精神分裂症患者外周血淋巴细胞对PHA刺激反应中的作用]

Zh Nevropatol Psikhiatr Im S S Korsakova. 1978;78(1):80-6.

7

[The cell cycles of schizophrenic patients peripheral blood lymphocytes (DNA synthesis in a culture of schizophrenic patients peripheral blood leukocytes stimulated by PHA)].[精神分裂症患者外周血淋巴细胞的细胞周期（PHA刺激的精神分裂症患者外周血白细胞培养中的DNA合成）]

Zh Nevropatol Psikhiatr Im S S Korsakova. 1974;74(8):1191-5.

8

[Adhesive lymphocytes in the peripheral blood of schizophrenic patients].[精神分裂症患者外周血中的黏附淋巴细胞]

Zh Nevropatol Psikhiatr Im S S Korsakova. 1977;77(7):1053-7.

9

[Proliferative response of schizophrenic patient's peripheral blood lymphocytes].[精神分裂症患者外周血淋巴细胞的增殖反应]

Zh Nevropatol Psikhiatr Im S S Korsakova. 1978;78(6):867-71.

10

[Role of schizophrenic patients' serum in the altered osmotic resistance of their lymphocytes].[精神分裂症患者血清在其淋巴细胞渗透压抗性改变中的作用]

Zh Nevropatol Psikhiatr Im S S Korsakova. 1981;81(7):1018-21.

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