Rowe J W, Caralis D G
Angiology. 1978 Jul;29(7):562-8. doi: 10.1177/000331977802900709.
Three unrelated men with Fabry's disease (angiokeratoma corporis diffusum universale) and accelerated atrioventricular conduction are described. AQn His bundle electrogram in one patient who reported episodes of tachycardia demonstrated a prolonged deflection preceding the ventricular complex. This deflection is thought to represent an abnormal His bundle potential, possible resulting from glycolipid deposition. In the second patient the PR interval decreased from 0.18 to 0.11 second during 10 years, and in the third patient it decreased from 0.12 to 0.10 seconds during 13 years. Accelerated atrioventricular conduction may develop in Fabry's disease.
本文描述了三名患有法布里病（弥漫性全身血管角质瘤）且伴有房室传导加速的无血缘关系男性患者。一名报告有心动过速发作的患者进行的希氏束电图检查显示，心室复合波之前有一个延长的波峰。这个波峰被认为代表异常的希氏束电位，可能是由糖脂沉积所致。第二名患者的PR间期在10年中从0.18秒降至0.11秒，第三名患者的PR间期在13年中从0.12秒降至0.10秒。法布里病可能会出现房室传导加速。
