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与风疹疫苗接种相关的弥漫性脊髓炎。

Diffuse myelitis associated with rubella vaccination.

作者信息

Holt S, Hudgins D, Krishnan K R, Critchley E M

出版信息

Br Med J. 1976 Oct 30;2(6043):1037-8. doi: 10.1136/bmj.2.6043.1037.

Abstract

Two patients who had received live rubella vaccine developed diffuse myelitis shortly afterwards. Neither patient fully recovered her motor function. In one patients the time between vaccination and development of neurological signs was rather too short to indicate definitely a causal relation. Nevertheless, the chronological association is suggestive, and other observations of such an association may strengthen the suspicion that rubella vaccination may occasionally cause severe neurological damage.

摘要

两名接种了风疹活疫苗的患者在接种后不久发生了弥漫性脊髓炎。两名患者的运动功能均未完全恢复。其中一名患者从接种疫苗到出现神经症状的时间间隔过短,无法明确表明存在因果关系。然而,从时间顺序上看两者存在关联,这种关联具有一定提示性,并且其他类似关联的观察结果可能会增强对风疹疫苗接种偶尔可能导致严重神经损伤的怀疑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea16/1689082/69601b7eaeb8/brmedj00541-0017-a.jpg

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