Goette D K, Carson T E
Cancer. 1976 Oct;38(4):1498-502. doi: 10.1002/1097-0142(197610)38:4<1498::aid-cncr2820380409>3.0.co;2-#.
Seven adult men with biopsy-confirmed erythroplasia of Queyrat (EQ) were cured of their disease with topically applied 5-fluorouracil (5-FU) under occlusion. Post-treatment biopsy specimens revealed normal histologic findings and recurrence-free follow-up periods extended up to 70 months. It is suggested that topical 5-FU is the treatment of choice for histologically confirmed EQ because of its superior results compared with thoseof surgery or radiation therapy. Our view is corroborated by several single case reports of EQ similarly treated.
七名经活检确诊为Queyrat增殖性红斑（EQ）的成年男性，通过局部应用5-氟尿嘧啶（5-FU）并加以封闭治疗，疾病得以治愈。治疗后的活检标本显示组织学检查结果正常，无复发生存期长达70个月。由于与手术或放射治疗相比，局部应用5-FU效果更佳，因此建议其为组织学确诊的EQ的首选治疗方法。数篇关于EQ类似治疗的单病例报告证实了我们的观点。
