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输卵管癌——综述

Fallopian tube carcinoma--a review.

作者信息

Ng P, Lawton F

机构信息

Department of Obstetrics and Gynaecology, King's College Hospital, Denmark Hill, London, United Kingdom.

出版信息

Ann Acad Med Singap. 1998 Sep;27(5):693-7.

PMID:9919342
Abstract

Although a common site of metastases, primary fallopian tube carcinoma comprises only 0.3% of all gynaecological malignancies. Presenting symptoms are variable and non-specific, with preoperative diagnosis rarely entertained. The FIGO system assigns nearly two-thirds of patients to stage I or II and is based on surgical staging criteria similar to those for ovarian cancer. Likewise, management is based on that for ovarian cancer-radical debulking followed by platinum-based combination chemotherapy. Five-year survival for patients with disease confined to the tube at diagnosis (stage I) is only about 60% and only 10% of patients with advanced disease will be cured.

摘要

尽管输卵管是转移的常见部位,但原发性输卵管癌仅占所有妇科恶性肿瘤的0.3%。其临床表现多样且不具特异性,术前很少考虑进行诊断。国际妇产科联盟(FIGO)系统将近三分之二的患者归为Ⅰ期或Ⅱ期,该分期基于与卵巢癌相似的手术分期标准。同样,治疗方法也基于卵巢癌的治疗——根治性肿瘤细胞减灭术,随后进行铂类联合化疗。诊断时疾病局限于输卵管(Ⅰ期)的患者5年生存率仅约为60%,晚期疾病患者只有10%能被治愈。

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MRP2 (ABCC2, cMOAT) expression in nuclear envelope of primary fallopian tube cancer cells is a new unfavorable prognostic factor.MRP2(ABCC2,cMOAT)在原发性输卵管癌细胞核膜中的表达是新的预后不良因素。
Arch Gynecol Obstet. 2013 Mar;287(3):563-70. doi: 10.1007/s00404-012-2589-7. Epub 2012 Nov 8.
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Primary papillary adenocarcinoma of the fallopian tube with ovarian metastasis.伴有卵巢转移的原发性输卵管乳头状腺癌。
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