[静脉注射因子 XIII 和凝血活酶后的抗凝系统]
[The anticoagulant system following intravenous administration of factor XIII and thromboplastin].
作者信息
Liapina L A, Ul'ianov A M, Zhitnikova E S
出版信息
Fiziol Zh SSSR Im I M Sechenova. 1976 Aug;62(8):1166-70.
PMID:992139
Abstract
The inactivated factor XIII does not change the functional state of the anticoagulating system. The i.v. administration of thromboplastin activates the anticoagulating system in rats which cannot be prevented by an artificial rise of the titre of the inactivated factor XIII in blood. The i.v. injections of the secondary adreanlin-heparin--fibrinogen complex with higher level of the factor XIII is followed by a sharp increase in the functional activity of the anticoagulating system.
摘要
灭活的因子 XIII 不会改变抗凝系统的功能状态。静脉注射凝血活酶会激活大鼠的抗凝系统，而血液中灭活因子 XIII 效价的人为升高并不能阻止这种激活。静脉注射具有较高水平因子 XIII 的继发性肾上腺素 - 肝素 - 纤维蛋白原复合物后，抗凝系统的功能活性会急剧增加。
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