Karakoz I, Hasek M, Kohoutová L
Folia Biol (Praha). 1976;22(5):304-11.
Duck immune sera that are capable of destroying the tolerated skin allografts require the presence of functional host's lymphoid cells for a successful course of the rejection reaction. The effective sera are not able to destroy the grafts in birds surgically bursectomized or thymectomized at hatching. This deficiency can be repaired by thymic, not bursal, implants in bursectomized or thymectomized graft hosts. Similarly, measurements of the radioactivity after application of 125I-labelled gamma globulin to allografted or autografted ducklings confirm a major role of the bursa of Fabricius and thymus in the destruction of the tolerated skin allografts by immune serum.
能够破坏被耐受的皮肤同种异体移植物的鸭免疫血清，在排斥反应的成功过程中需要有功能的宿主淋巴细胞的存在。有效的血清无法破坏在孵化时接受手术切除法氏囊或胸腺的鸟类的移植物。这种缺陷可以通过在切除法氏囊或胸腺的移植物宿主中植入胸腺而非法氏囊来修复。同样，给同种异体移植或自体移植的小鸭注射125I标记的γ球蛋白后测量放射性，证实了法氏囊和胸腺在免疫血清破坏被耐受的皮肤同种异体移植物中起主要作用。
