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历史自然生育人群中的结婚季、成功受孕及时性及头胎性别比例——存在性别依赖性早期妊娠丢失的证据?

Marriage season, promptness of successful pregnancy and first-born sex ratio in a historical natural fertility population--evidence for sex-dependent early pregnancy loss?

作者信息

Nonaka K, Desjardins B, Charbonneau H, Légaré J, Miura T

机构信息

Department of Hygiene, Teikyo University School of Medicine, Tokyo, Japan.

出版信息

Int J Biometeorol. 1998 Dec;42(2):89-92. doi: 10.1007/s004840050090.

DOI:10.1007/s004840050090
PMID:9923201
Abstract

We investigated population-based vital records of the seventeenth and eighteenth century French Canadian population to assess the effects of marriage season on the outcome of the first births under natural fertility conditions (n = 21,698 marriages). Promptness of the first successful conception after marriage differed according to marriage season; the proportion of marriages with a marriage-first birth interval of 8.0-10.0 months was lowest (34%) for marriages in August-October (P = 0.001). Although the male/female sex ratio of the babies born with an interval of 8.0-10.0 months was generally higher (1.10) than those with an interval of 10.0-24.0 months (1.05), the marriages in August-October resulted in a significantly reduced sex ratio (0.96) among only the prompt conceptions (P = 0.026). We discuss whether this seasonal reduction of the sex ratio could be partly explained by a clustered pregnancy loss of male zygotes in early pregnancy.

摘要

我们调查了17和18世纪法裔加拿大人群基于人口的重要记录,以评估婚姻季节对自然生育条件下首次生育结局的影响(n = 21,698例婚姻)。婚后首次成功受孕的及时性因婚姻季节而异;8.0 - 10.0个月婚姻首次生育间隔的婚姻比例在8月至10月的婚姻中最低(34%)(P = 0.001)。尽管8.0 - 10.0个月间隔出生的婴儿的男/女性别比通常高于10.0 - 24.0个月间隔出生的婴儿(1.10对1.05),但8月至10月的婚姻仅在快速受孕中导致显著降低的性别比(0.96)(P = 0.026)。我们讨论了这种性别比的季节性降低是否可以部分由妊娠早期男性合子的聚集性妊娠丢失来解释。

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