西班牙呼吸道感染患者中1113株肺炎链球菌分离株的抗菌药物耐药性：一项为期1年（1996 - 1997年）的多中心监测研究结果。西班牙呼吸道病原体监测小组
Antimicrobial resistance of 1,113 Streptococcus pneumoniae isolates from patients with respiratory tract infections in Spain: results of a 1-year (1996-1997) multicenter surveillance study. The Spanish Surveillance Group for Respiratory Pathogens.
作者信息
Baquero F, García-Rodríguez J A, García de Lomas J, Aguilar L
机构信息
Microbiology Department, Ramón y Cajal Hospital, Madrid, Spain.
出版信息
Antimicrob Agents Chemother. 1999 Feb;43(2):357-9. doi: 10.1128/AAC.43.2.357.
Abstract
A nationwide susceptibility surveillance of 1,113 Streptococcus pneumoniae isolates was carried out and found the following percentages of resistance: cefuroxime, 46%; penicillin, 37%; macrolides, 33%; aminopenicillins, 24%; cefotaxime, 13%; and ceftriaxone, 8%. A significant (P < 0.05) seasonality pattern for beta-lactam antibiotics was observed. Resistance to macrolides was higher (P < 0.05) in middle-ear samples. Higher percentages of resistance to cefuroxime and macrolides were observed among penicillin-intermediate and -resistant strains, whereas high frequencies of resistance to aminopenicillins and expanded-spectrum cephalosporins were observed only among penicillin-resistant strains.
摘要
对1113株肺炎链球菌分离株进行了全国性药敏监测，结果发现耐药百分比情况如下：头孢呋辛，46%；青霉素，37%；大环内酯类，33%；氨基青霉素，24%；头孢噻肟，13%；头孢曲松，8%。观察到β-内酰胺类抗生素存在显著的（P<0.05）季节性模式。中耳样本中对大环内酯类的耐药性更高（P<0.05）。在青霉素中介和耐药菌株中观察到对头孢呋辛和大环内酯类的耐药百分比更高，而仅在青霉素耐药菌株中观察到对氨基青霉素和广谱头孢菌素的高耐药频率。
相似文献
1
Antimicrobial resistance of 1,113 Streptococcus pneumoniae isolates from patients with respiratory tract infections in Spain: results of a 1-year (1996-1997) multicenter surveillance study. The Spanish Surveillance Group for Respiratory Pathogens.西班牙呼吸道感染患者中1113株肺炎链球菌分离株的抗菌药物耐药性：一项为期1年（1996 - 1997年）的多中心监测研究结果。西班牙呼吸道病原体监测小组
Antimicrob Agents Chemother. 1999 Feb;43(2):357-9. doi: 10.1128/AAC.43.2.357.
2
Streptococcus pneumoniae in community-acquired respiratory tract infections in Spain: the impact of serotype and geographical, seasonal and clinical factors on its susceptibility to the most commonly prescribed antibiotics. The Spanish Surveillance Group for Respiratory Pathogens.西班牙社区获得性呼吸道感染中的肺炎链球菌：血清型以及地理、季节和临床因素对其对最常用抗生素敏感性的影响。西班牙呼吸道病原体监测小组
J Antimicrob Chemother. 2000 Oct;46(4):557-64. doi: 10.1093/jac/46.4.557.
3
[Antimicrobial susceptibility of community-acquired respiratory tract pathogens isolated from class B hospitals in China during 2013 and 2014].[2013年至2014年期间从中国乙类医院分离出的社区获得性呼吸道病原体的抗菌药敏性]
Zhonghua Jie He He Hu Xi Za Zhi. 2016 Jan;39(1):30-7. doi: 10.3760/cma.j.issn.1001-0939.2016.01.009.
4
Resistance surveillance of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis isolated in Asia and Europe, 1997-1998.1997 - 1998年亚洲和欧洲分离出的肺炎链球菌、流感嗜血杆菌和卡他莫拉菌的耐药性监测
J Antimicrob Chemother. 2000 Apr;45(4):457-66. doi: 10.1093/jac/45.4.457.
5
E test for studying in vitro activity of seven antimicrobial agents against penicillin-susceptible and penicillin-resistant pneumococci.E试验用于研究七种抗菌药物对青霉素敏感和耐药肺炎球菌的体外活性。
Chin Med J (Engl). 2000 Jul;113(7):628-31.
6
Resistance surveillance of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis isolated in the United States, 1997-1998.1997 - 1998年美国分离出的肺炎链球菌、流感嗜血杆菌和卡他莫拉菌的耐药性监测
J Antimicrob Chemother. 1999 Dec;44(6):749-59. doi: 10.1093/jac/44.6.749.
7
In vitro activity of cefditoren and other antimicrobial agents against 288 Streptococcus pneumoniae and 220 Haemophilus influenzae clinical strains isolated in Zaragoza, Spain.头孢妥仑及其他抗菌药物对西班牙萨拉戈萨分离出的288株肺炎链球菌和220株流感嗜血杆菌临床菌株的体外活性。
Diagn Microbiol Infect Dis. 2008 Oct;62(2):210-5. doi: 10.1016/j.diagmicrobio.2008.06.007. Epub 2008 Aug 20.
8
9
Penicillin-resistant and -intermediate Streptococcus pneumoniae in Saudi Arabia.沙特阿拉伯的耐青霉素和中度青霉素敏感性肺炎链球菌
J Chemother. 2000 Apr;12(2):134-7. doi: 10.1179/joc.2000.12.2.134.
10
Antimicrobial resistance among lower respiratory tract isolates of Streptococcus pneumoniae: results of a 1992-93 western Europe and USA collaborative surveillance study. The Alexander Project Collaborative Group.肺炎链球菌下呼吸道分离株的抗菌药物耐药性：1992 - 1993年西欧和美国合作监测研究结果。亚历山大项目协作组
J Antimicrob Chemother. 1996 Jul;38 Suppl A:71-84. doi: 10.1093/jac/38.suppl_a.71.
引用本文的文献
1
Improved penicillin susceptibility of Streptococcus pneumoniae and increased penicillin consumption in Japan, 2013-18.2013-2018 年日本肺炎链球菌青霉素敏感性提高和青霉素消耗量增加。
PLoS One. 2020 Oct 22;15(10):e0240655. doi: 10.1371/journal.pone.0240655. eCollection 2020.
2
Seasonality of antimicrobial resistance rates in respiratory bacteria: A systematic review and meta-analysis.呼吸道细菌中抗菌药物耐药率的季节性：系统评价和荟萃分析。
PLoS One. 2019 Aug 15;14(8):e0221133. doi: 10.1371/journal.pone.0221133. eCollection 2019.
3
An evolutionary model to predict the frequency of antibiotic resistance under seasonal antibiotic use, and an application to .一种用于预测季节性抗生素使用情况下抗生素耐药性频率的进化模型及其应用于…… （原文最后不完整）
Proc Biol Sci. 2017 May 31;284(1855). doi: 10.1098/rspb.2017.0679.
4
Drug resistance in community-acquired respiratory tract infections: role for an emerging antibacterial.社区获得性呼吸道感染中的耐药性：新兴抗菌药物的作用。
Infect Drug Resist. 2010;3:35-43. doi: 10.2147/idr.s8964. Epub 2010 Jun 18.
5
Overexpression of patA and patB, which encode ABC transporters, is associated with fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae.在肺炎链球菌的临床分离株中，编码 ABC 转运蛋白的 patA 和 patB 的过度表达与氟喹诺酮类药物耐药有关。
Antimicrob Agents Chemother. 2011 Jan;55(1):190-6. doi: 10.1128/AAC.00672-10. Epub 2010 Oct 11.
6
Antimicrobial resistance among respiratory pathogens in Spain: latest data and changes over 11 years (1996-1997 to 2006-2007).西班牙呼吸道病原体的抗生素耐药性：11 年间（1996-1997 年至 2006-2007 年）的最新数据和变化。
Antimicrob Agents Chemother. 2010 Jul;54(7):2953-9. doi: 10.1128/AAC.01548-09. Epub 2010 May 3.
7
The efflux pump inhibitor reserpine selects multidrug-resistant Streptococcus pneumoniae strains that overexpress the ABC transporters PatA and PatB.外排泵抑制剂利血平可筛选出过度表达ABC转运蛋白PatA和PatB的多重耐药肺炎链球菌菌株。
Antimicrob Agents Chemother. 2008 May;52(5):1677-85. doi: 10.1128/AAC.01644-07. Epub 2008 Mar 24.
8
Macrolide resistance in Streptococcus pneumoniae: Fallacy or fact?肺炎链球菌对大环内酯类药物的耐药性：谬误还是事实？
Can J Infect Dis. 2002 Jan;13(1):13-6. doi: 10.1155/2002/501543.
9
Gram-positive cocci infections in intensive care: guide to antibacterial selection.重症监护中的革兰氏阳性球菌感染：抗菌药物选择指南
Drugs. 2006;66(6):751-68. doi: 10.2165/00003495-200666060-00003.
10
Trends in drug resistance, serotypes, and molecular types of Streptococcus pneumoniae colonizing preschool-age children attending day care centers in Lisbon, Portugal: a summary of 4 years of annual surveillance.葡萄牙里斯本日托中心学龄前儿童肺炎链球菌定植的耐药性、血清型和分子类型趋势：4年年度监测总结
J Clin Microbiol. 2005 Mar;43(3):1285-93. doi: 10.1128/JCM.43.3.1285-1293.2005.
本文引用的文献
1
Erythromycin resistance of Streptococcus pyogenes in Madrid.马德里化脓性链球菌的红霉素耐药性
Pediatr Infect Dis J. 1998 Jun;17(6):470-3. doi: 10.1097/00006454-199806000-00006.
2
Invasive antibiotic-resistant Streptococcus pneumoniae in children in Madrid.
Pediatr Infect Dis J. 1998 Mar;17(3):252-5. doi: 10.1097/00006454-199803000-00018.
3
Antibiotic resistance in Spain: what can be done? Task Force of the General Direction for Health Planning of the Spanish Ministry of Health.西班牙的抗生素耐药性：该如何应对？西班牙卫生部卫生规划总司特别工作组
Clin Infect Dis. 1996 Oct;23(4):819-23. doi: 10.1093/clinids/23.4.819.
4
Streptococcus pneumoniae and Streptococcus pyogenes resistant to macrolides but sensitive to clindamycin: a common resistance pattern mediated by an efflux system.对大环内酯类耐药但对克林霉素敏感的肺炎链球菌和化脓性链球菌：一种由外排系统介导的常见耐药模式。
Antimicrob Agents Chemother. 1996 Aug;40(8):1817-24. doi: 10.1128/AAC.40.8.1817.
5
Antibiotic resistance and serotypes of Streptococcus pneumoniae at Birmingham Public Health Laboratory, 1989-94.1989 - 1994年伯明翰公共卫生实验室肺炎链球菌的抗生素耐药性及血清型
J Infect. 1996 Jul;33(1):17-22. doi: 10.1016/s0163-4453(96)92681-x.
6
Penicillin-resistant Streptococcus pneumoniae in acute otitis media: risk factors, susceptibility patterns and antimicrobial management.急性中耳炎中耐青霉素肺炎链球菌：危险因素、药敏模式及抗菌治疗
Pediatr Infect Dis J. 1995 Sep;14(9):751-9. doi: 10.1097/00006454-199509000-00005.
7
Penicillin resistance among Streptococcus pneumoniae in Europe.欧洲肺炎链球菌中的青霉素耐药性。
Diagn Microbiol Infect Dis. 1994 Jul;19(3):157-61. doi: 10.1016/0732-8893(94)90059-0.
8
Pneumococcal bacteraemia: 325 episodes diagnosed at St Thomas's Hospital.肺炎球菌血症：在圣托马斯医院诊断出325例病例。
Br Med J (Clin Res Ed). 1985 Feb 16;290(6467):505-8. doi: 10.1136/bmj.290.6467.505.
9
Serotype distribution and antimicrobial resistance of Streptococcus pneumoniae isolates causing systemic infections in Spain, 1979-1989.1979 - 1989年西班牙引起全身感染的肺炎链球菌分离株的血清型分布及耐药性
Rev Infect Dis. 1991 Jan-Feb;13(1):56-60. doi: 10.1093/clinids/13.1.56.
10
Trends in antimicrobial resistance of clinical isolates of Streptococcus pneumoniae in Bellvitge Hospital, Barcelona, Spain (1979-1990).西班牙巴塞罗那贝尔维奇医院肺炎链球菌临床分离株的抗菌药物耐药性趋势（1979 - 1990年）
Clin Infect Dis. 1992 Jul;15(1):99-105. doi: 10.1093/clinids/15.1.99.
Zotero 插件