Vidard M N, Girard N, Chauzy C, Delpech B, Delpech A, Maunoury R, Laumonier R
C R Acad Hebd Seances Acad Sci D. 1978 Jun 19;286(24):1837-40.
Absence of GFA in established cell lines from glioblastomas promped us to look for this protein from the first replication of malignant cells in vitro and in following subcultrues. Our results show that GFA disappeared during the first twelve replications, often before the fifth replication. No correlation was observed with a morphological transformation of the cells.
在成胶质细胞瘤的既定细胞系中缺乏胶质纤维酸性蛋白（GFA），这促使我们从恶性细胞在体外的首次复制以及后续传代培养中寻找这种蛋白质。我们的结果表明，GFA在最初的十二次复制过程中消失了，通常在第五次复制之前。未观察到与细胞形态转变的相关性。
