[The cardiotoxic properties of kordaron in acute myocardial ischemia and infarct].

Cardiodepressive and arrhythmogenic properties of cordarone were studied on cat in conditions of experimental acute ischemia and myocardial infarction upon intravenous infusion. The obtained results showed an increase cordarone cardiotoxicity and arrhythmogenic properties in conditions of myocardial infarction. No reliable difference was observed in dynamics of cordarone-induced changes in ECG parameters in animals with myocardial ischemia of various duration and intact animals.