Combined oral and vaginal treatment of severe vulvovaginitis during childhood.

STUDY OBJECTIVE

To evaluate the efficacy and safety of combined oral and vaginal administration of antibiotics.

DESIGN

Treatment and follow-up examination of 54 cases of severe vulvovaginitis.

SETTING

Division of Pediatric and Adolescent' Gynecology, Second Department of Obstetrics and Gynecology, University of Athens, Greece.

PARTICIPANTS

Girls aged 1-10 years seen at the clinic of the above-listed institution.

INTERVENTIONS

Vaginal application of antibiotics.

MAIN OUTCOME MEASURES

Vaginal culture and vaginoscopy.

RESULTS

Treatment achieved microbial eradication in 51 of 54 patients (94%). In most patients, relief of symptoms was achieved after 2-3 days. No adverse effects were reported.

CONCLUSIONS

Treatment was highly effective and simple to administer, and no complications were observed. A further advantage of this approach is the shorter duration of treatment.