Marík J, Capek A, Králícek J
J Chromatogr. 1976 Nov 17;128(1):1-11. doi: 10.1016/s0021-9673(00)84025-x.
The silylation of C4-C11 omega-amino acids and their hydrochlorides was carried out with N,O-bis(trimethylsilyl)acetamide. Di-TMS and tri-TMS derivatives were formed in the silylation of the hydrochlorides. The formation of the two derivatives is dependent on the reaction conditions, and the conditions under which only derivative arises reproducibly, are reported. This finding may be utilized in the quantitative analysis of amino acids.
使用N,O-双(三甲基硅基)乙酰胺对C4 - C11 ω-氨基酸及其盐酸盐进行硅烷化反应。盐酸盐在硅烷化反应中形成了二-TMS和三-TMS衍生物。这两种衍生物的形成取决于反应条件，并且报告了仅可重复产生一种衍生物的条件。这一发现可用于氨基酸的定量分析。
