Moro P L, Checkley W, Gilman R H, Lescano G, Bonilla J J, Silva B, Garcia H H
Department of Pathology, Universidad Peruana Cayetano Heredia, Lima, Peru.
Am J Gastroenterol. 1999 Jan;94(1):153-8. doi: 10.1111/j.1572-0241.1999.00787.x.
Cholelithiasis is a common problem in hospitals of the Peruvian Andes; however, its prevalence in Andean communities is unknown. To estimate the prevalence of gallstone disease in this locale, we conducted a cross-sectional community study in three high-altitude Peruvian rural villages (i.e., > 3000 m above sea level).
We examined 911 volunteers > 15 yr of age from three villages for gallstone disease by history and ultrasonography. Risk factors for gallstone disease were examined in 382 volunteers from one village.
The age-adjusted prevalence of gallstone disease ranged from 4-10% in men and from 18-20% in women. Women had significantly higher age-adjusted prevalence rates than did men. The prevalence of gallstone disease increased significantly with age and decreased significantly with alcohol consumption. Although not statistically significant, we found a positive association between gallstone disease and body mass index.
The results of this study indicate that gallstone disease, commonly perceived as a disease of the developed world, is also a common problem in high-altitude Peruvian communities.
胆结石在秘鲁安第斯地区的医院中是一个常见问题；然而，其在安第斯社区的患病率尚不清楚。为了估计该地区胆结石疾病的患病率，我们在秘鲁三个高海拔乡村（即海拔超过3000米）开展了一项横断面社区研究。
我们通过病史询问和超声检查，对来自三个村庄的911名15岁以上志愿者进行了胆结石疾病检查。在来自一个村庄的382名志愿者中，对胆结石疾病的危险因素进行了调查。
经年龄调整后的胆结石疾病患病率在男性中为4%-10%，在女性中为18%-20%。经年龄调整后的患病率女性显著高于男性。胆结石疾病的患病率随年龄显著增加，随饮酒量显著降低。虽然无统计学意义，但我们发现胆结石疾病与体重指数之间存在正相关。
本研究结果表明，胆结石疾病通常被认为是发达国家的疾病，在秘鲁高海拔社区也是一个常见问题。
