Brett A S, Shaw S V
Department of Medicine, University of South Carolina School of Medicine, Richland Memorial Hospital, Columbia, USA.
Am J Gastroenterol. 1999 Jan;94(1):267-8. doi: 10.1111/j.1572-0241.1999.00812.x.
A 34-yr-old woman developed simultaneous pancreatitis and hepatitis following exposure to trimethoprim-sulfamethoxazole (TMP/SMX). The episode occurred 4 yr after a previous episode of hepatitis associated with TMP/SMX. This patient represents the second case of concurrent TMP/SMX-induced pancreatitis and hepatitis reported in the literature. However, it is the first in which the adverse reaction was documented following an inadvertent rechallenge with the drug.
一名34岁女性在服用甲氧苄啶-磺胺甲恶唑(TMP/SMX)后同时发生胰腺炎和肝炎。此次发作发生在之前一次与TMP/SMX相关的肝炎发作4年后。该患者是文献报道中第二例同时发生TMP/SMX诱发的胰腺炎和肝炎的病例。然而,这是第一例在无意中再次使用该药物后记录到不良反应的病例。