Fischer F
Klin Monbl Augenheilkd. 1976 Jun;168(6):784-7.
Material of research: 350 cases of diabetes mellitus. The time between the manifestation of diabetes mellitus and the onset of retinopathy is reduced in two cases: with diabetes manifesting itself (a) at the age of puberty, (b) after the age of fifty. The retinopathy appears as "retinopathia simplex" (in all its different subvarieties) and as "retinopathia proliferans". Out investigation showed a gradual decrease in the benign forms of the retinopathia simplex with advancing years--from twenty to sixty--of diabetic manifestation, with retinopathia proliferans simultaneously gaining ground. With diabetes manifesting from sixty on, retinopathia proliferans dwindles to insignificance; there remains an indefinite form of retinopathia simplex.
350例糖尿病患者。有两例糖尿病患者从糖尿病出现到视网膜病变发作的时间缩短：（a）青春期发病的糖尿病，（b）五十岁以后发病的糖尿病。视网膜病变表现为“单纯性视网膜病”（及其所有不同亚型）和“增殖性视网膜病”。我们的调查显示，随着糖尿病发病年限从二十年增加到六十年，单纯性视网膜病的良性形式逐渐减少，而增殖性视网膜病则同时增多。六十岁以后发病的糖尿病，增殖性视网膜病逐渐减少至微不足道；剩下一种不明确的单纯性视网膜病形式。
