Encke A, Best A
Langenbecks Arch Chir. 1976 Nov 15;342:527-32. doi: 10.1007/BF01267421.
The primary lesion is widely excised under a general anesthetic. The resulting defect is covered by a free graft. Prophylactic lymph-node dissection seems to be reasonable for stage-I melanoma with deep invasion (microstage III-V) according to recent investigations. Stage II is an absolute indication. Stage III patients received an individual palliative therapy. The value of additional measures is not yet clearly defined.
在全身麻醉下广泛切除原发性病变。所形成的缺损用游离移植片覆盖。根据最近的研究，对于有深部浸润（微分期III - V）的I期黑色素瘤，预防性淋巴结清扫似乎是合理的。II期是绝对指征。III期患者接受个体化姑息治疗。额外措施的价值尚未明确界定。
