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肝包虫病的诊断与治疗

Diagnosis and treatment of liver hydatid disease.

作者信息

Uravic M, Stimac D, Lenac T, Ivanis N, Petrosic N, Rubinic M, Skarpa A

机构信息

Surgical Clinic, Department of Digestive Surgery, Clinical Hospital Center Rijeka, Croatia.

出版信息

Hepatogastroenterology. 1998 Nov-Dec;45(24):2265-9.

PMID:9951908
Abstract

BACKGROUND/AIMS: Human echinococcosis is endemic in some areas of the world, including Mediterranean countries. The liver is the most frequent seat of echinococcosis, involved in about 70% of cases. Because there is still no effective medical therapy, surgery remains the treatment of choice.

METHODOLOGY

Twenty-seven patients operated on for liver hydatid disease between 1990 and 1995 were analyzed and compared with results obtained from a study undertaken at our clinic between 1960 and 1988.

RESULTS

The diagnosis was established by typical case history, clinical features and laboratory tests, of which imaging methods proved most informative. Radical procedures (total pericystectomy and liver resection) seem to be too aggressive for treatment. Marsupialization and drainage were mostly abandoned, because of high morbidity rates.

CONCLUSIONS

Among surgical procedures used at our clinic, evacuation of the cyst with partial excision of the pericyst and omentoplasty resulted in the lowest morbidity and, thereupon, the shortest post-operative hospital stay and the best clinical results.

摘要

背景/目的:人体包虫病在世界上一些地区呈地方性流行,包括地中海国家。肝脏是包虫病最常见的发病部位,约70%的病例累及肝脏。由于目前仍没有有效的药物治疗方法,手术仍是首选的治疗方式。

方法

对1990年至1995年间因肝包虫病接受手术治疗的27例患者进行分析,并与1960年至1988年间在我们诊所进行的一项研究结果进行比较。

结果

通过典型的病史、临床特征和实验室检查确诊,其中影像学方法提供的信息最多。根治性手术(完全囊肿切除术和肝切除术)似乎对治疗来说过于激进。由于发病率高,袋形缝合术和引流术大多被放弃。

结论

在我们诊所采用的外科手术中,囊肿排空并部分切除囊肿周围组织及网膜成形术导致的发病率最低,因此术后住院时间最短,临床效果最佳。

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