Sogawa M, Moro H, Tsuchida M, Shinonaga M, Ohzeki H, Hayashi J
Department of Thoracic and Cardiovascular Surgery, Niigata University School of Medicine, Japan.
ASAIO J. 1999 Jan-Feb;45(1):90-3. doi: 10.1097/00002480-199901000-00020.
The purpose of this study was to evaluate the possibility of surgical treatment of an atrial septal defect in the beating heart without cardiopulmonary bypass. The first step was to develop an endocardioscope that permitted observation of the inside of the beating heart. To visualize the inside of the beating heart, the tip of the endoscope was covered with a glass adapter. The endocardioscope was inserted through the right atrial appendage in eight beagles. The atrial septum, foramen ovale, coronary sinus, tricuspid valve, and chordae tendineae were identified without hemodynamic derangement. The second step was to attempt to close the foramen ovale with clips or staplers. We were able to close the foramen ovale with these devices, but a safer, easier device is needed. The endocardioscope we developed should prove to be a useful tool for minimally invasive surgical treatment of heart diseases, such as atrial septal defect.
本研究的目的是评估在不停跳心脏且不进行体外循环的情况下手术治疗房间隔缺损的可能性。第一步是研制一种心内膜镜，以便能够观察跳动心脏的内部情况。为了可视化跳动心脏的内部，内镜尖端覆盖有玻璃适配器。在心内膜镜通过八只比格犬的右心耳插入。在血流动力学无紊乱的情况下识别出房间隔、卵圆孔、冠状窦、三尖瓣和腱索。第二步是尝试用夹子或吻合器关闭卵圆孔。我们能够用这些装置关闭卵圆孔，但需要一种更安全、更简便的装置。我们研制的心内膜镜应被证明是用于诸如房间隔缺损等心脏病微创外科治疗的有用工具。
