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患有神经疾病儿童的血铅水平。

Blood lead levels in children with neurological disorders.

作者信息

Kumar A, Dey P K, Singla P N, Ambasht R S, Upadhyay S K

机构信息

Department of Paediatrics, Faculty of Science, Banaras Hindu University, Varanasi, India.

出版信息

J Trop Pediatr. 1998 Dec;44(6):320-2. doi: 10.1093/tropej/44.6.320.

Abstract

Blood lead levels were measured by atomic absorption spectrometry in 82 children suffering from various neurological disorders (cerebral palsy 42, seizure disorders 35, acute encephalopathy of unknown origin 5) and in 28 healthy children, aged 1 to 12 years. Mean blood lead levels were 11.96 +/- 10.97 micrograms/dl in control children and 19.30 +/- 17.65 micrograms/dl in children with neurological disorders. A significant number of control children as well as those who had neurological disorders were found to have blood lead concentrations of > or = 10 micrograms/dl and > or = 20 micrograms/dl, the cut-off limits for lead poisoning and medical evaluation, respectively. Blood lead levels were, statistically, elevated in children with cerebral palsy compared to controls. Children with pica behaviour exhibited higher blood lead concentrations.

摘要

采用原子吸收光谱法对82名患有各种神经疾病(42例脑瘫、35例癫痫症、5例不明原因的急性脑病)的1至12岁儿童以及28名健康儿童进行血铅水平检测。对照组儿童的平均血铅水平为11.96±10.97微克/分升,患有神经疾病的儿童为19.30±17.65微克/分升。发现相当数量的对照组儿童以及患有神经疾病的儿童血铅浓度分别≥10微克/分升和≥20微克/分升,这分别是铅中毒和医学评估的临界值。统计学上,脑瘫儿童的血铅水平高于对照组。有异食癖行为的儿童血铅浓度更高。

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