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[磁共振尿路造影:超快速屏气序列在梗阻性尿路病中的临床应用。个人经验]

[Magnetic resonance pyelography: clinical use of ultrafast breath-hold sequences in obstructive uropathy. Personal experience].

作者信息

Blandino A, Scribano E, Gaeta M, Minutoli F, Famulari C, Macrì A, Pandolfo I

机构信息

Istituto di Scienze Radiologiche, dell'Università, Messina.

出版信息

Radiol Med. 1998 Oct;96(4):353-9.

PMID:9972215
Abstract

INTRODUCTION

We investigated the diagnostic yield of MR pyelography (MRP) performed with two ultrafast breath-hold sequences in obstructive uropathy patients.

MATERIAL AND METHODS

Thirty-four patients with US demonstration of urinary tract dilation were examined with MRP at 1.5 T and with a standard body coil. HASTE sequences (TE 66, ETL 128, FA 180 degrees, 1 NEX, MA 240 x 256, slice thickness 4 mm, TA 13 s) were always performed and 26/34 patients were also examined with single-shot TSE sequences (TE 1100, ETL 240, FA 150 degrees, 1 NEX, slice thickness 7 cm, MA 240 x 256, FS, TA 7 s); 20/34 patients were given 500 mL superparamagnetic contrast agent (Lumirem). MRP findings were interpreted independently by two radiologists and analyzed for image quality, the presence/absence of dilation, the obstruction grade (mild, moderate, severe), site (intrarenal; ureteropelvic junction; proximal, mid-, distal ureter; indeterminate) and cause (intrinsic obstruction from a stone or other conditions; stenosis; indeterminate cause). The sensitivity, specificity, positive and negative predictive values for the detection of urinary tract dilation were calculated for each reviewer and interobserver agreement was calculated with the k analysis relative to the presence, grade, site and cause of urinary tract dilation.

RESULTS

MRP examinations were considered technically adequate in all cases by both observers. As for the presence of urinary tract dilation, the values were 100% for the first observer and 97%, 100%, 100%, and 95%, respectively, for the second observer. Interobserver agreement was .98 for dilation presence (excellent), .80 for dilation degree (excellent), .62 for dilation site (good) and finally .69 for dilation cause (good).

DISCUSSION AND CONCLUSIONS

MRP performed with the ultrafast breath-hold technique provides very good results in diagnosing urinary tract dilation, as well as the obstruction grade, site and cause, with results equal or even superior to those of non-breath-hold sequences. Ultrafast MRP lasts only 10 minutes, meaning it occupies the magnet shortly and costs less: it can be thus considered a routine alternative to conventional diagnostic imaging, especially ivp, in the evaluation of obstructive uropathy.

摘要

引言

我们研究了在梗阻性尿路病患者中使用两种超快屏气序列进行磁共振尿路造影(MRP)的诊断效能。

材料与方法

对34例经超声显示尿路扩张的患者进行了1.5T磁共振尿路造影检查,使用标准体部线圈。总是执行HASTE序列(TE 66,ETL 128,FA 180度,1次激励,矩阵240×256,层厚4mm,采集时间13s),34例患者中的26例还使用了单次激发快速自旋回波序列(TE 1100,ETL 240,FA 150度,1次激励,层厚7cm,矩阵240×256,脂肪抑制,采集时间7s);34例患者中的20例给予了500ml超顺磁性对比剂(Lumirem)。两名放射科医生独立解读MRP检查结果,并分析图像质量、有无扩张、梗阻程度(轻度、中度、重度)、部位(肾内;肾盂输尿管连接处;输尿管近端、中段、远端;不确定)及病因(结石或其他情况引起的内在梗阻;狭窄;病因不确定)。计算每位阅片者检测尿路扩张的敏感度、特异度、阳性预测值和阴性预测值,并采用K分析计算观察者间关于尿路扩张的存在、程度、部位及病因的一致性。

结果

两位观察者均认为所有病例的MRP检查在技术上是充分的。对于尿路扩张的存在情况,第一位观察者的检测值为100%,第二位观察者的检测值分别为97%、100%、100%和95%。观察者间关于扩张存在情况的一致性为0.98(优秀),关于扩张程度的一致性为0.80(优秀),关于扩张部位的一致性为0.62(良好),关于扩张病因的一致性为0.69(良好)。

讨论与结论

采用超快屏气技术进行的MRP在诊断尿路扩张以及梗阻程度、部位和病因方面取得了很好的结果,其结果等同于甚至优于非屏气序列。超快MRP仅持续10分钟,意味着它占用磁体的时间短且成本较低:因此在评估梗阻性尿路病时,它可被视为传统诊断成像尤其是静脉肾盂造影的常规替代方法。

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