经皮微波凝固疗法治疗肝细胞癌的疗效
[Curative effect of percutaneous microwave coagulation therapy for hepatocellular carcinoma].
作者信息
Chen Yi, Chen Han, Wu Mengchao, Zhou Weiping, Wei Gongtian, Wang Peijun, Li Xiaoyan
机构信息
Department of Ultrasound Intervention, Eastern Hepatobiliary Hospital, Second Military Medical University, Shanghai 200438, China.
出版信息
Zhonghua Zhong Liu Za Zhi. 2002 Jan;24(1):65-7.
OBJECTIVE
To observe the curative effect of percutaneous microwave coagulation therapy (PMCT) with 2450 MHz microwave antenna for hepatocellular carcinoma.
METHODS
Under local or epidural anesthesia, a thin percutaneous microwave antenna was introduced with ultrasound guidance into the tumor in the liver for thermo-coagulation.
RESULTS
Among the 97 hepatic cancer lesions in 52 patients, 61(62.9%) with phi < 3 cm were coagulated once. In follow-up of 6-12 months of these lesions, 57(93.4%) showed no recurrence by CT or MRI. Thirty-six (37.1%) with 3 cm < phi < 5 cm coagulated twice showed that 27 (75.0%) gave CR and 9 (25.0%) gave PR by CT or MRI in follow up of 6 months. There were no serious clinical side effects or complications in the PMCT patients.
CONCLUSION
Percutaneous microwave coagulation therapy gives good curative effect on liver tumor with phi < 3 cm. It is partly effective on lesions 3 cm < phi < 5 cm.
目的
观察采用2450兆赫微波天线行经皮微波凝固治疗（PMCT）对肝细胞癌的疗效。
方法
在局部或硬膜外麻醉下，在超声引导下将一根细的经皮微波天线插入肝脏肿瘤内进行热凝固。
结果
52例患者的97个肝癌病灶中，直径<3厘米的61个（62.9%）病灶一次凝固。对这些病灶进行6至12个月的随访，通过CT或MRI检查，57个（93.4%）无复发。直径3厘米<直径<5厘米的36个（37.1%）病灶凝固两次，在6个月的随访中，通过CT或MRI检查显示27个（75.0%）达到完全缓解（CR），9个（25.0%）达到部分缓解（PR）。PMCT患者未出现严重的临床副作用或并发症。
结论
经皮微波凝固治疗对直径<3厘米的肝肿瘤疗效良好。对直径3厘米<直径<5厘米的病灶有一定疗效。
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