Wiedermann G, Ambrosch F
Bull World Health Organ. 1979;57(4):625-9.
The usefulness of an immunization programme can be evaluated by comparing either risks and benefits or costs and benefits. By means of special formulae, the benefit-cost ratio and the benefit-cost difference can be calculated for monovalent and bivalent vaccines. An analysis of combined measles-mumps immunization in Austria showed that this measure is highly profitable economically. Since employed mothers are allowed one week's vacation each year to nurse a sick child, this affects the calculations. Including the cost of the "nursing vacation" among the benefits that would be realized following an immunization programme, the estimated benefit-cost ratio is 4.48; if the cost of the "nursing vacation" is omitted the ratio is 2.65. The estimated annual benefit-cost differences are AS 1681.90 and AS 672.85, respectively, per child. Twelve years after the beginning of a programme to immunize 100 000 1-year-old children per year (corresponding roughly to the birth rate in Austria) an amount of AS 528 million would be saved if the "nursing vacation" is included in the calculations and an amount of AS 63 million if it is not.
免疫计划的效用可以通过比较风险与收益或成本与收益来评估。借助特殊公式,可以计算单价和双价疫苗的效益成本比及效益成本差额。对奥地利麻疹 - 腮腺炎联合免疫的分析表明,这项措施在经济上具有很高的收益。由于职业母亲每年可享有一周假期来照料生病的孩子,这会影响计算结果。若将“护理假期”的成本计入免疫计划后的收益中,估计的效益成本比为4.48;若忽略“护理假期”的成本,该比率为2.65。估计每个孩子每年的效益成本差额分别为1681.90奥地利先令和672.85奥地利先令。在一项每年为10万名1岁儿童进行免疫的计划(大致相当于奥地利的出生率)开始12年后,如果将“护理假期”纳入计算,将节省5.28亿奥地利先令;若不纳入,则节省6300万奥地利先令。