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一例重度地方性氟中毒病例中骨骼的力学性能和密度

Mechanical properties and density of bone in a case of severe endemic fluorosis.

作者信息

Evans F G, Wood J L

出版信息

Acta Orthop Scand. 1976 Oct;47(5):489-95. doi: 10.3109/17453677608988726.

DOI:10.3109/17453677608988726
PMID:998183
Abstract

Mechanical properties of 25 standardized specimens of compact bone from a 45-year-old man with extreme endemic fluorosis were compared with similar specimens of nonfluorotic bone. Data from dry and wet tested specimens were compared. Tensile strength, strain, energy absorbed to failure, and modulus of elasticity were reduced in fluorotic specimens while compressive strength, strain and energy were increased in both wet and dry specimens. Compressive properties exceeded tensile properties. Drying increased tensile and compressive strength and modulus but decreased tensile and compressive strength and energy absorbed. Dry specimens tended to follow Hooke's Law but wet specimens exhibited visco-elastic behavior. Wet fluorotic specimens had lower tensile properties but higher compressive properties and were more dense than fresh human compact bone.

摘要

对一名患有重度地方性氟中毒的45岁男性的25个标准化致密骨标本的力学性能,与非氟中毒骨的类似标本进行了比较。对干燥和湿润测试标本的数据进行了比较。氟中毒标本的拉伸强度、应变、破坏时吸收的能量和弹性模量降低,而湿润和干燥标本的抗压强度、应变和能量均增加。抗压性能超过拉伸性能。干燥增加了拉伸和抗压强度及模量,但降低了拉伸和抗压强度及吸收的能量。干燥标本倾向于遵循胡克定律,而湿润标本表现出粘弹性行为。湿润的氟中毒标本拉伸性能较低,但抗压性能较高,且比新鲜人类致密骨更致密。

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