Wallis S M, Walker-Smith J
Acta Paediatr Scand. 1976 Nov;65(6):749-51. doi: 10.1111/j.1651-2227.1976.tb18014.x.
Although perianal ulceration is common in Crohn's disease, extensive perineal ulceration particularly in children is rare. The case history is presented of a child who developed progressive hypertrophy of the vulva and ulceration of the groins at the age of 11 years but diagnosis of Crohn' s disease was delayed for 21 months. Treatment with steroids and azathioprine has induced a successful remission but difficulty has been experienced in reducing the steroid dosage.
虽然肛周溃疡在克罗恩病中很常见,但广泛的会阴溃疡,尤其是在儿童中却很罕见。本文介绍了一名11岁儿童的病例,该儿童出现外阴进行性肥大和腹股沟溃疡,但克罗恩病的诊断延迟了21个月。使用类固醇和硫唑嘌呤治疗已成功诱导缓解,但在减少类固醇剂量方面遇到了困难。