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Lymphocyte sensitivity to glucocorticoids.

作者信息

BenEzra D, Ticho U, Sachs U

出版信息

Am J Ophthalmol. 1976 Dec;82(6):866-70. doi: 10.1016/0002-9394(76)90062-3.

DOI:10.1016/0002-9394(76)90062-3
PMID:998702
Abstract

We evaluated the possibility of identifying patients with open-angle glaucoma based on the in vitro behavior of their lymphocytes in the presence of glucocorticoids. Our results do not support the hypothesis that lymphocytes from patients with open-angle glaucoma, as compared to those from normal subjects, are more sensitive to the presence of corticosteroids in vitro. In addition, the degree of inhibition induced by glucocorticoids was closely related to the amount of activation of the lymphocyte membrane induced by different concentrations of phytohemagglutinin. Our results indicated that this may be a general phenomenon rather than one that is specific to a particular ophthalmological condition.

摘要

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引用本文的文献

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2
Ocular hypertension.高眼压症
Br Med J. 1978 May 13;1(6122):1230-1.
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Steroid-induced glaucoma: A. Persistent elevation of intraocular pressure B. Histopathological aspects.类固醇性青光眼：A. 眼压持续升高 B. 组织病理学方面
Trans Am Ophthalmol Soc. 1977;75:353-81.
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Primary open-angle glaucoma and sensitivity to corticosteroids in vitro.原发性开角型青光眼与体外对皮质类固醇的敏感性
Trans Am Ophthalmol Soc. 1977;75:339-52.