Orko R, Malmivuo J
Ann Clin Res. 1976 Aug;8(4):248-53.
Immediate haemodynamic changes during electrical cardioversion were compared in 30 patients anaesthetized either with thiopental or with Althesin. The systolic arterial pressure, heart rate, stroke and cardiac indices were measured before atropine premedication, after atropine, during anaesthesia, and 3 and 10 minutes after defibrillation. The stroke index was estimated by transthoracic impedance method. Both anaesthetics caused a significant but similar decrease in systolic arterial pressure. The cardiac index remained relatively stable in both groups during all stages of the procedure. Atropine induced an expected increase in heart rate and a decrease in stroke index. while both variables tended to approach the baseline values after cardioversion with no difference between thiopental and althesin groups. No significant difference in the haemodynamic response to cardioversion was seen in patients with heart volumes exceeding 650 ml/m2 BSA as compared to those with smaller hearts. It is concluded that both thiopental and althesin can be considered as safe anaesthetics for cardioversion.
对30例分别用硫喷妥钠或安泰酮麻醉的患者在电复律期间的即时血流动力学变化进行了比较。在阿托品术前用药前、用药后、麻醉期间以及除颤后3分钟和10分钟测量收缩动脉压、心率、每搏量和心脏指数。每搏量指数通过经胸阻抗法估算。两种麻醉剂均导致收缩动脉压显著但相似地降低。在手术的所有阶段，两组的心脏指数均保持相对稳定。阿托品使心率预期增加，每搏量指数降低。而在复律后两个变量均趋于接近基线值，硫喷妥钠组和安泰酮组之间无差异。与心脏较小的患者相比，心脏容积超过650 ml/m²体表面积的患者在复律时的血流动力学反应无显著差异。结论是硫喷妥钠和安泰酮均可被视为复律的安全麻醉剂。
