Pfahl F, Rouffy J, Duperrat B, Puissant A
Ann Dermatol Syphiligr (Paris). 1976;103(1):15-22.
The hyperlipoproteinaemia truly characteristic of psoriasis is the type IV or major endogenous hypertriglyceridaemia. It is found in 39 p. 100 of patients with psoriasis as compared to 18 p. 100 of our controls (though 6 p. 100 of the French population according to Turpin and De Gennes). It appears to be definitely genotypic, environmental factors playing only a minor role. This study would tend to integrate psoriasis into the category of the metabolic diseases, coinciding with the notion of troubles with glucose metabolism in psoriatics, since it is now accepted that 80 p. 100 of type IV hyperlipoproteinaemias are pre-diabetic.
银屑病真正典型的高脂蛋白血症是IV型或主要内源性高甘油三酯血症。在39%的银屑病患者中可发现这种情况,相比之下,我们的对照组中这一比例为18%(不过根据图尔平和德热内的数据,法国人群中的比例为6%)。它似乎肯定是由基因型决定的,环境因素只起次要作用。这项研究倾向于将银屑病归入代谢疾病范畴,这与银屑病患者存在糖代谢问题的观点相符,因为现在公认80%的IV型高脂蛋白血症处于糖尿病前期。