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[溶菌酶抗菌活性的特征]

[Characteristics of the antimicrobial activity of lysozyme].

作者信息

Bukharin O V, Usviatsov B Ia, Matiiash I N, Pastukhova G V, Prianishnikova L I

出版信息

Antibiotiki. 1976 Sep;21(9):805-8.

PMID:999264
Abstract

The antibacterial effect of lysozyme manufactured in the USSR was studied with respect to 1496 pathogenic strains of different microbial species. It was found that the percentage of the organisms sensitive to lysozyme among the total number of the microbes tested was not high and ranged within 1.5-3 except streptococci (21.7 per cent). Significant differences in the minimum bacteriostatic concentration (from 0.0006 to 10 mg/ml) with respect to both different microbial species and organisms belonging to the same microbial species were found. By the level of the antibacterial activity the Soviet lysozyme was not inferior to the Italian preparation. With respect to streptococci the Soviet lysozyme was more active.

摘要

对苏联生产的溶菌酶针对1496株不同微生物种类的致病菌株的抗菌效果进行了研究。结果发现,在所测试的微生物总数中,对溶菌酶敏感的生物体百分比不高,除链球菌(21.7%)外,范围在1.5%至3%之间。发现不同微生物种类以及属于同一微生物种类的生物体在最低抑菌浓度(从0.0006至10毫克/毫升)方面存在显著差异。就抗菌活性水平而言,苏联的溶菌酶不逊色于意大利的制剂。就链球菌而言,苏联的溶菌酶活性更高。

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