Pokidova N V, Zhuravleva T P, Zudin B I, Panichkina G S, Verenchikova Ia V
Antibiotiki. 1976 Sep;21(9):826-8.
The levels of lysozyme in the serum and organs of Shienshilla male rabbits infected with Nico-s treponema were determined. The studies showed that the lues infection affected the factors of non-specific immunity, which was evident from the changes in the lysozyme titer. Administration of benzylpenicillin resulted in a marked decrease in the lysozyme titer in all cases. The experiments are indicative of advisability of studying the use of crystalline lysozyme in combination with antibiotics for increasing the efficacy of therapy of syphilitic infection.
测定了感染尼古梅毒螺旋体的朝鲜雄性兔血清和器官中的溶菌酶水平。研究表明,梅毒感染影响非特异性免疫因素,这从溶菌酶滴度的变化中可以明显看出。在所有情况下,注射苄青霉素都会导致溶菌酶滴度显著降低。这些实验表明,研究使用结晶溶菌酶与抗生素联合使用以提高梅毒感染治疗效果是可取的。