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人体受试者吸入的汞(HG - 197、HG - 203)蒸气的清除情况。

Clearance of mercury (HG-197, HG-203) vapor inhaled by human subjects.

作者信息

Hursh J B, Cherian M G, Clarkson T W, Vostal J J, Mallie R V

出版信息

Arch Environ Health. 1976 Nov-Dec;31(6):302-9. doi: 10.1080/00039896.1976.10667240.

DOI:10.1080/00039896.1976.10667240
PMID:999343
Abstract

Five human subjects inhaled a mixture of stable and radioactive mercury vapor for periods of 14 to 24 minutes. The subjects retained an average of 74% of that inhaled. Evidence is submitted to show that the retention occurred almost entirely in the alveoli. For 3 days after exposure, the exhaled breath was passed at intervals through activated charcoal traps for sampling periods of 10 to 35 minutes. The data indicated that an average of 7% of the retained mercury was lost in the expired breath, with a half time of 18 hours. Examination of the subjects in a whole body counter yielded average half times for mercury clearance from different parts of the body as follows: lung, 1.7 days; head, 21 days; kidney region, 64 days; chest, 43 days; and whole body, 58 days.

摘要

五名人体受试者吸入稳定态和放射性汞蒸气的混合物,持续时间为14至24分钟。受试者平均保留了吸入量的74%。有证据表明,汞的留存几乎全部发生在肺泡中。在接触后的3天里,呼出的气体每隔一段时间通过活性炭捕集器,采样时间为10至35分钟。数据表明,留存汞的平均7%在呼气中损失,半衰期为18小时。在全身计数器中对受试者进行检查,得出汞从身体不同部位清除的平均半衰期如下:肺部,1.7天;头部,21天;肾脏区域,64天;胸部,43天;全身,58天。

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