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吗啡、氯丙嗪和氯氮卓对休克诱导的基础皮肤电导率变化的影响。

Effects of morphine, chlorpromazine and chlordiazepoxide on shock-induced changes in basal skin conductance.

作者信息

Jones B E, Prada J A

出版信息

Arch Int Pharmacodyn Ther. 1976 Oct;223(2):265-70.

PMID:999409
Abstract

Chlorpromazine (12.5 and 25 mg/70 kg, i.m.) and chlordiazepoxide (25 and 50 mg/70 kg, i.m.) were compared with morphine (15 and 30 mg/70 kg, i.m.) and placebo in their effects on electric shock-induced increases in basal skin conductance. Morphine and chlorpromazine attenuated the increase compared with placebo, while chlordiazepoxide did not. None of the treatments produced reliable effects on the phasic responses to the stimuli.

摘要

将氯丙嗪(12.5毫克/70千克和25毫克/70千克,肌肉注射)、氯氮卓(25毫克/70千克和50毫克/70千克,肌肉注射)与吗啡(15毫克/70千克和30毫克/70千克,肌肉注射)及安慰剂相比较,观察它们对电击诱发的基础皮肤电导增加的影响。与安慰剂相比,吗啡和氯丙嗪可减弱这种增加,而氯氮卓则无此作用。所有处理对刺激的相位反应均未产生可靠影响。

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