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药物与受罚反应。五、药物对由反应依赖性和反应独立性电击所抑制的反应的影响。

Drugs and punished responding. V. Effects of drugs on responding suppressed by response-dependent and response-independent electric shock.

作者信息

McMillan D E, Leander J D

出版信息

Arch Int Pharmacodyn Ther. 1975 Jan;213(1):22-7.

PMID:1156015
Abstract

A procedure was used where responses by a pigeon produced electric shock both to that pigeon (response-dependent shock) and to another pigeon (response-independent shock) working under the same schedule of food presentation. Both response-dependent and response-independent shock partially suppressed responding. Pentobarbital, chlordiazepoxide and ethanol increased responding suppressed by response-dependent shock, but only pentobarbital increased responding suppressed by response-independent shock. Morphine, d-amphetamine, chlorpromazine, doxepin, and pentazocine either had no effect, or further decreased rates of responding suppressed by response-dependent or response-independent shock.

摘要

采用了一种程序,在这种程序中,鸽子的反应会对自身(反应依赖性电击)以及另一只按照相同食物呈现时间表工作的鸽子(反应非依赖性电击)产生电击。反应依赖性电击和反应非依赖性电击都部分抑制了反应。戊巴比妥、氯氮卓和乙醇增加了被反应依赖性电击抑制的反应,但只有戊巴比妥增加了被反应非依赖性电击抑制的反应。吗啡、右旋苯丙胺、氯丙嗪、多塞平和喷他佐辛要么没有效果,要么进一步降低了被反应依赖性或反应非依赖性电击抑制的反应速率。

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