从正常甲状腺、单纯性甲状腺肿和毒性甲状腺肿中提取的19S甲状腺球蛋白在聚丙烯酰胺平板凝胶等电聚焦中的不同行为。
Different behaviour of 19S thyroglobulin extracted from normal thyroid, simple goitre and toxic goitre in polyacrylamide slab gel isoelectric focusing.
作者信息
Massi G, Crivelli F
出版信息
Acta Endocrinol (Copenh). 1978 Oct;89(2):296-302. doi: 10.1530/acta.0.0890296.
PMID:99941
Abstract
19S thyroglobulin (19S TG) was isolated from normal thyroids, simple goitres and one case of toxic goitre (Graves' disease). With isoelectric focusing on polyacrylamide gel slabs (pH 4--6) several bands for each specimen were detected. The migration patterns of the toxic goitre 19S TG were clearly different from the patterns of normal 19S TG and simple goitre 19S TG.
摘要
从正常甲状腺、单纯性甲状腺肿以及1例毒性甲状腺肿（格雷夫斯病）中分离出19S甲状腺球蛋白（19S TG）。通过在聚丙烯酰胺凝胶板上进行等电聚焦（pH 4 - 6），检测到每个样本有几条条带。毒性甲状腺肿19S TG的迁移模式与正常19S TG和单纯性甲状腺肿19S TG的模式明显不同。
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