Tarach J S
Acta Histochem. 1978;62(1):32-43. doi: 10.1016/S0065-1281(78)80103-2.
The combined electronmicroscopic and cytochemical investigations of lysosomes and peroxisomes of a rat cardiac muscle were carried out in various duration time of the alloxan diabetes. The analysis of cytochemical reactions with DAB, confirming the existence of peroxisomes in rat heart muscle revealed that the state of experimental alloxan diabetes did not at all affect either cytochemical or morphological image of peroxisomes. In comparison with the control group, in all 3 experimental groups cytochemical reaction to acid phosphatase markedly pointed to the increase in number and size of electron-dense bodies (lysosomes) with positive reaction. This state may most probably result both from local and general organism disturbances in metabolism, induced by particular experimental conditions.
在四氧嘧啶糖尿病的不同持续时间，对大鼠心肌的溶酶体和过氧化物酶体进行了电子显微镜和细胞化学联合研究。用二氨基联苯胺（DAB）进行细胞化学反应分析，证实大鼠心肌中存在过氧化物酶体，结果显示实验性四氧嘧啶糖尿病状态根本不影响过氧化物酶体的细胞化学或形态学图像。与对照组相比，在所有3个实验组中，酸性磷酸酶的细胞化学反应明显表明，呈阳性反应的电子致密体（溶酶体）数量增加且体积增大。这种状态很可能是由特定实验条件引起的局部和全身机体代谢紊乱导致的。
