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[脑瘫病因与临床表现之间关系的统计学研究]

[Statistical study of the relationships between the etiology and clinical picture of cerebral palsy].

作者信息

Doyon F, Laiter N, Gagnard L, Rumeau-Rouquette C

出版信息

Arch Fr Pediatr. 1978 Jun-Jul;35(6):595-606.

PMID:100077
Abstract

846 children with cerebral palsy were examined and 642 were selected for a statistical study by correspondence analysis. The aim was to identify without any prior assumptions, the relationships between the aetiological factors and the clinical findings. The study was completed by conventional statistical analysis of 584 of the cases. Small birth weight and a history of abnormal pregnancies was associated with a cerebral palsy affecting both legs, and often with a squint. Resuscitation was associated with athetosis and abnormalities of posture and behaviour. If the resuscitation lasted for more than 15 minutes or there were certain problems during delivery, severe abnormalities of both arms and major speech difficulties were observed. Resuscitation for less than 15 minutes or for an unknown time or intractable vomiting during pregnancy was associated with quadraplegia. Hemiplegia was related to post natal events but the aetiology was not always known. Foeto-maternal incompatibility was associated with athetosis, deafness, severe speech problems and ophthalmoplegias.

摘要

对846名脑瘫患儿进行了检查,并通过对应分析选取了642名患儿进行统计研究。目的是在没有任何先验假设的情况下,确定病因因素与临床发现之间的关系。该研究通过对584例病例进行常规统计分析得以完成。低出生体重和异常妊娠史与影响双腿的脑瘫相关,且常伴有斜视。复苏与手足徐动症以及姿势和行为异常有关。如果复苏持续超过15分钟或分娩期间存在某些问题,则会观察到双臂严重异常和严重的言语困难。复苏时间少于15分钟或时间不明或孕期顽固性呕吐与四肢瘫痪有关。偏瘫与产后事件有关,但病因并不总是明确的。母婴血型不合与手足徐动症、耳聋、严重言语问题和眼肌麻痹有关。

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