Bonnah R A, Wong H, Loosmore S M, Schryvers A B
Department of Microbiology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada T2N 4N1.
Infect Immun. 1999 Mar;67(3):1517-20. doi: 10.1128/IAI.67.3.1517-1520.1999.
Pathogenic members of the family Neisseriaceae produce specific receptors to acquire iron from their host's lactoferrin and transferrin. Recently, putative Moraxella catarrhalis lactoferrin receptor genes and a third open reading frame (lbpB, lbpA, and orf3) were cloned and sequenced. We describe the preliminary characterization of isogenic mutants deficient in LbpB, LbpA, or Orf3 protein.
奈瑟菌科的致病成员会产生特定受体,以便从宿主的乳铁蛋白和转铁蛋白中获取铁。最近,已克隆并测序了假定的卡他莫拉菌乳铁蛋白受体基因及第三个开放阅读框(lbpB、lbpA和orf3)。我们描述了缺乏LbpB、LbpA或Orf3蛋白的同基因突变体的初步特征。