Danielsen T E, Lang rd S, Andersen A
The National Institute of Occupational Health, PO Box 8149 Dep., 0033 Oslo, Norway.
Int J Occup Environ Health. 1998 Apr-Jun;4(2):85-8. doi: 10.1179/oeh.1998.4.2.85.
The incidence of lung cancer among 428 shipyard welders exposed for more than ten years to welding fumes was investigated. The welders were examined for siderosis by the Directorate of Labor Inspection in 1975. The present study was a follow-up based on historical information from the Norwegian registry of dust-exposed workers. Twenty-three welders with siderosis, and 156 welders working at the same shipyards as the siderosis cases were studied as sub-cohorts. There was no loss on follow-up. The observation period was 1976 through 1992. There were 32 cases of cancer from all causes vs 41.3 expected. A nonsignificant excess of lung cancer was observed; 10 cases vs 6.5 expected. The incidence of lung cancer was highest for the welders with more than 30 years since first exposure (7 cases vs 4.1 expected). The sub-cohort of welders with siderosis had no case of lung cancer vs 0.5 expected. These welders were assumed to have experienced high exposure levels for welding fumes. The morbidity of cancer from all causes was low for this small group of blue-collar workers, but the incidence of lung cancer was slightly increased. The increase was not attributable to welders with siderosis. Smoking and asbestos exposure are potential confounders.
对428名接触焊接烟雾超过十年的造船厂焊工的肺癌发病率进行了调查。1975年，劳动监察局对这些焊工进行了铁尘肺检查。本研究是基于挪威粉尘接触工人登记处的历史信息进行的随访。将23名患有铁尘肺的焊工以及与铁尘肺病例在同一造船厂工作的156名焊工作为亚队列进行研究。随访过程中无失访情况。观察期为1976年至1992年。所有原因导致的癌症病例有32例，预期为41.3例。观察到肺癌有非显著性的超额发生；实际10例，预期6.5例。首次接触后超过30年的焊工肺癌发病率最高（实际7例，预期4.1例）。患有铁尘肺的焊工亚队列中无肺癌病例，预期为0.5例。假定这些焊工接触到了高水平的焊接烟雾。这一小群蓝领工人所有原因导致的癌症发病率较低，但肺癌发病率略有增加。这种增加并非由患有铁尘肺的焊工导致。吸烟和石棉接触是潜在的混杂因素。
